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MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice

High plasma cholesterol levels are a major risk factor for atherosclerosis. Plasma cholesterol can be reduced by inhibiting lipoprotein production; however, this is associated with steatosis. Previously we showed that lentivirally mediated hepatic expression of microRNA-30c (miR-30c) reduced hyperli...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Irani, Sara, Pan, Xiaoyue, Peck, Bailey C. E., Iqbal, Jahangir, Sethupathy, Praveen, Hussain, M. Mahmood
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000085/
https://ncbi.nlm.nih.gov/pubmed/27365390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.728451
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