Neonatal treatment with scopolamine butylbromide prevents metabolic dysfunction in male rats

We tested whether treatment with a cholinergic antagonist could reduce insulin levels in early postnatal life and attenuate metabolic dysfunctions induced by early overfeeding in adult male rats. Wistar rats raised in small litters (SLs, 3 pups/dam) and normal litters (NLs, 9 pups/dam) were used in...

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Vydáno v:Sci Rep
Hlavní autoři: Malta, Ananda, Souza, Aline Amenencia de, Ribeiro, Tatiane Aparecida, Francisco, Flávio Andrade, Pavanello, Audrei, Prates, Kelly Valério, Tófolo, Laize Peron, Miranda, Rosiane Aparecida, Oliveira, Júlio Cezar de, Martins, Isabela Peixoto, Previate, Carina, Gomes, Rodrigo Mello, Franco, Claudinéia Conationi da Silva, Natali, Maria Raquel Marçal, Palma-Rigo, Kesia, Mathias, Paulo Cezar de Freitas
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999897/
https://ncbi.nlm.nih.gov/pubmed/27561682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30745
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