Neonatal treatment with scopolamine butylbromide prevents metabolic dysfunction in male rats

We tested whether treatment with a cholinergic antagonist could reduce insulin levels in early postnatal life and attenuate metabolic dysfunctions induced by early overfeeding in adult male rats. Wistar rats raised in small litters (SLs, 3 pups/dam) and normal litters (NLs, 9 pups/dam) were used in...

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Pubblicato in:Sci Rep
Autori principali: Malta, Ananda, Souza, Aline Amenencia de, Ribeiro, Tatiane Aparecida, Francisco, Flávio Andrade, Pavanello, Audrei, Prates, Kelly Valério, Tófolo, Laize Peron, Miranda, Rosiane Aparecida, Oliveira, Júlio Cezar de, Martins, Isabela Peixoto, Previate, Carina, Gomes, Rodrigo Mello, Franco, Claudinéia Conationi da Silva, Natali, Maria Raquel Marçal, Palma-Rigo, Kesia, Mathias, Paulo Cezar de Freitas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999897/
https://ncbi.nlm.nih.gov/pubmed/27561682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30745
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