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The Role of the C-Clamp in Wnt-Related Colorectal Cancers

T-cell Factor/Lymphoid Enhancer Factor (TCF/LEF) transcription factors are major regulators of Wnt targets, and the products of the TCF7 and TCF7L2 genes have both been implicated in the progression of colorectal cancer in animal models and humans. TCFs recognize specific DNA sequences through their...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Ravindranath, Aditi J., Cadigan, Ken M.
Format: Artigo
Language:Inglês
Published: MDPI 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999783/
https://ncbi.nlm.nih.gov/pubmed/27527215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8080074
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