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A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria

Fatty acid metabolism is an important feature of the pathogenicity of Mycobacterium tuberculosis during infection. Consumption of fatty acids requires regulation of carbon flux bifurcation between the oxidative TCA cycle and the glyoxylate shunt. In Escherichia coli, flux bifurcation is regulated by...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Murima, Paul, Zimmermann, Michael, Chopra, Tarun, Pojer, Florence, Fonti, Giulia, Dal Peraro, Matteo, Alonso, Sylvie, Sauer, Uwe, Pethe, Kevin, McKinney, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999502/
https://ncbi.nlm.nih.gov/pubmed/27555519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12527
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