Effects of Single and Combined Losartan and Tempol Treatments on Oxidative Stress, Kidney Structure and Function in Spontaneously Hypertensive Rats with Early Course of Proteinuric Nephropathy

Oxidative stress has been widely implicated in both hypertension and chronic kidney disease (CKD). Hypertension is a major risk factor for CKD progression. In the present study we have investigated the effects of chronic single tempol (membrane-permeable radical scavenger) or losartan (angiotensin I...

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Publicado en:PLoS One
Autores principales: Karanovic, Danijela, Grujic-Milanovic, Jelica, Miloradovic, Zoran, Ivanov, Milan, Jovovic, Djurdjica, Vajic, Una-Jovana, Zivotic, Maja, Markovic-Lipkovski, Jasmina, Mihailovic-Stanojevic, Nevena
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999198/
https://ncbi.nlm.nih.gov/pubmed/27560781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161706
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