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A scale‐down mimic for mapping the process performance of centrifugation, depth and sterile filtration

In the production of biopharmaceuticals disk‐stack centrifugation is widely used as a harvest step for the removal of cells and cellular debris. Depth filters followed by sterile filters are often then employed to remove residual solids remaining in the centrate. Process development of centrifugatio...

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Bibliografiska uppgifter
I publikationen:Biotechnol Bioeng
Huvudupphovsmän: Joseph, Adrian, Kenty, Brian, Mollet, Michael, Hwang, Kenneth, Rose, Steven, Goldrick, Stephen, Bender, Jean, Farid, Suzanne S., Titchener‐Hooker, Nigel
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999036/
https://ncbi.nlm.nih.gov/pubmed/26927621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25967
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