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A scale‐down mimic for mapping the process performance of centrifugation, depth and sterile filtration
In the production of biopharmaceuticals disk‐stack centrifugation is widely used as a harvest step for the removal of cells and cellular debris. Depth filters followed by sterile filters are often then employed to remove residual solids remaining in the centrate. Process development of centrifugatio...
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| Publicado no: | Biotechnol Bioeng |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4999036/ https://ncbi.nlm.nih.gov/pubmed/26927621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25967 |
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