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A scale‐down mimic for mapping the process performance of centrifugation, depth and sterile filtration

In the production of biopharmaceuticals disk‐stack centrifugation is widely used as a harvest step for the removal of cells and cellular debris. Depth filters followed by sterile filters are often then employed to remove residual solids remaining in the centrate. Process development of centrifugatio...

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Vydáno v:Biotechnol Bioeng
Hlavní autoři: Joseph, Adrian, Kenty, Brian, Mollet, Michael, Hwang, Kenneth, Rose, Steven, Goldrick, Stephen, Bender, Jean, Farid, Suzanne S., Titchener‐Hooker, Nigel
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999036/
https://ncbi.nlm.nih.gov/pubmed/26927621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25967
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