DNA methylation as an adjunct to histopathology to detect prevalent, inconspicuous dysplasia and early-stage neoplasia in Barrett’s esophagus

PURPOSE: Endoscopic surveillance of Barrett’s esophagus (BE) is problematic because dysplasia/early-stage neoplasia are frequently invisible and likely to be missed due to sampling bias. Molecular abnormalities may be more diffuse than dysplasia. The aim was therefore to test whether DNA methylation...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Alvi, Muhammad A, Liu, Xinxue, O’Donovan, Maria, Newton, Richard, Wernisch, Lorenz, Shannon, Nicholas B, Shariff, Kareem, di Pietro, Massimiliano, Bergman, Jacques J G H M, Ragunath, Krish, Fitzgerald, Rebecca C
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998953/
https://ncbi.nlm.nih.gov/pubmed/23243219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2880
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