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Lack of Influence of Substrate on Ligand Interaction with the Human Multidrug and Toxin Extruder, MATE1
Multidrug and toxin extruder (MATE) 1 plays a central role in mediating renal secretion of organic cations, a structurally diverse collection of compounds that includes ∼40% of prescribed drugs. Because inhibition of transport activity of other multidrug transporters, including the organic cation tr...
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| Publicado en: | Mol Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4998666/ https://ncbi.nlm.nih.gov/pubmed/27418674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.105056 |
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