Targeted Disruption of miR-17-92 Impairs Mouse Spermatogenesis by Activating mTOR Signaling Pathway

The miR-17-92 cluster and its 6 different mature microRNAs, including miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1, and miR-92a, play important roles in embryo development, immune system, kidney and heart development, adipose differentiation, aging, and tumorigenicity. Currently, increasing evidence...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Medicine (Baltimore)
Hauptverfasser: Xie, Raoying, Lin, Xiaolin, Du, Tao, Xu, Kang, Shen, Hongfen, Wei, Fang, Hao, Weichao, Lin, Taoyan, Lin, Xia, Qin, Yujuan, Wang, Huiyan, Chen, Lin, Yang, Sheng, Yang, Jie, Rong, Xiaoxiang, Yao, Kaitai, Xiao, Dong, Jia, Junshuang, Sun, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Health 2016
Schlagworte:
7300
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998608/
https://ncbi.nlm.nih.gov/pubmed/26886608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000002713
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