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Trastuzumab as a preoperative monotherapy does not inhibit HER2 downstream signaling in HER2-positive breast cancer

Human epidermal growth factor 2 (HER2) is overexpressed in 15–20% of breast carcinomas. The overexpression of HER2 was previously associated with a poor prognosis until the development of the first anti-HER2 therapy, trastuzumab, which drastically improves the prognosis of HER2-overexpressing breast...

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Sonraí Bibleagrafaíochta
Foilsithe in:Oncol Lett
Main Authors: Lion, Maëva, Harlé, Alexandre, Salleron, Julia, Ramacci, Carole, Campone, Mario, Merlin, Jean-Louis
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998521/
https://ncbi.nlm.nih.gov/pubmed/27602133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4891
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