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Occurrence of the alpha subunits of G proteins in cerebral cortex synaptic membrane and postsynaptic density fractions: modulation of ADP-ribosylation by Ca2+/calmodulin.

We have examined the isolated postsynaptic density (PSD) fraction for the presence of a G protein. First, we found specific binding of guanosine 5'-[gamma-[35S]thio]triphosphate to the PSD. Second, pertussis toxin-activated ADP-ribosylation of the isolated PSD fraction resulted in the appearance of...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wu, K, Nigam, S K, LeDoux, M, Huang, Y Y, Aoki, C, Siekevitz, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1992
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1326762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.18.8686
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