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Recombinant thrombomodulin for secondary thrombotic thrombocytopenic purpura
In the pathogenesis of thrombotic thrombocytopenic purpura (TTP), reductions in the enzyme activity of ADAMTS13, which cuts ultralarge von Willebrand multimers, generates shear stress on the microvascular endothelium, leading to platelet aggregation and the formation of a thrombus. ADAMTS13 activity...
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| Udgivet i: | Medicine (Baltimore) |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wolters Kluwer Health
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4998437/ https://ncbi.nlm.nih.gov/pubmed/27310951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000003712 |
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