Combination With Low-dose Dextromethorphan Improves the Effect of Amlodipine Monotherapy in Clinical Hypertension: A First-in-human, Concept-proven, Prospective, Dose-escalation, Multicenter Study

The combination of low rather than high dose of dextromethorphan (DXM) with amlodipine (AM) could improve blood pressure (BP) reduction in hypertensive animals. The study aimed to evaluate the feasibility of different doses of DXM combined with standard AM treatment in clinical hypertension. This wa...

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Dettagli Bibliografici
Pubblicato in:Medicine (Baltimore)
Autori principali: Yin, Wei-Hsian, Chen, Pei, Yeh, Hung-I, Wang, Kuo-Yang, Hung, Yi-Jen, Tseng, Wei-Kung, Wen, Ming-Shien, Wu, Tao-Cheng, Wu, Chau-Chung, Cheng, Shu-Meng, Chen, Jaw-Wen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer Health 2016
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3400
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998419/
https://ncbi.nlm.nih.gov/pubmed/27015224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000003234
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