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Identification and functional characterization of a TIA-1-related nucleolysin.

We recently reported the molecular cloning of a cytotoxic granule-associated RNA-binding protein designated TIA-1. The ability of recombinant TIA-1 to induce DNA fragmentation in permeabilized cells suggested that this protein is the granule component responsible for inducing apoptosis in cytolytic...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kawakami, A, Tian, Q, Duan, X, Streuli, M, Schlossman, S F, Anderson, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49984/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1326761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.18.8681
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