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Misoprostol Reverse Hippocampal Neuron Cyclooxygenase-2 Downstream Signaling Imbalance in Aluminum-Overload Rats

Although COX-2 inhibition in animal models of neurodegenerative diseases has shown neuroprotection, recent studies have revealed some serious side effects (ulcers, bleeding, fatal cerebrovascular diseases etc.) and the limited benefits of COX-2 inhibitors. A more focused approach is necessary to exp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Alzheimer Res
Hauptverfasser: Guo, Yuanxin, Lei, Wenjuan, Wang, Jianfeng, Hu, Xinyue, Wei, Yuling, Ji, Chaonan, Yang, Junqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997938/
https://ncbi.nlm.nih.gov/pubmed/27033056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1567205013666160401114601
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