In Vitro Assessment of the Antimicrobial Efficacy of Optimized Nitroglycerin-Citrate-Ethanol as a Nonantibiotic, Antimicrobial Catheter Lock Solution for Prevention of Central Line-Associated Bloodstream Infections

The rapid, broad-spectrum, biofilm-eradicating activity of the combination of 0.01% nitroglycerin, 7% citrate, and 20% ethanol and its potential as a nonantibiotic, antimicrobial catheter lock solution (ACLS) were previously reported. Here, a nitroglycerin-citrate-ethanol (NiCE) ACLS optimized for c...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Reitzel, Ruth A., Rosenblatt, Joel, Hirsh-Ginsberg, Cheryl, Murray, Kimberly, Chaftari, Anne-Marie, Hachem, Ray, Raad, Issam
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997850/
https://ncbi.nlm.nih.gov/pubmed/27297475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00254-16
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