Role of ABC and Solute Carrier Transporters in the Placental Transport of Lamivudine

Lamivudine is one of the antiretroviral drugs of choice for the prevention of mother-to-child transmission (MTCT) in HIV-positive women. In this study, we investigated the relevance of drug efflux transporters P-glycoprotein (P-gp) (MDR1 [ABCB1]), BCRP (ABCG2), MRP2 (ABCC2), and MATE1 (SLC47A1) for...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Ceckova, Martina, Reznicek, Josef, Ptackova, Zuzana, Cerveny, Lukas, Müller, Fabian, Kacerovsky, Marian, Fromm, Martin F., Glazier, Jocelyn D., Staud, Frantisek
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997848/
https://ncbi.nlm.nih.gov/pubmed/27401571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00648-16
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