Role of gyrB Mutations in Pre-extensively and Extensively Drug-Resistant Tuberculosis in Thai Clinical Isolates

DNA gyrase mutations are a major cause of quinolone resistance in Mycobacterium tuberculosis. We therefore conducted the first comprehensive study to determine the diversity of gyrase mutations in pre-extensively drug-resistant (pre-XDR) (n = 71) and extensively drug-resistant (XDR) (n = 30) Thai cl...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Disratthakit, Areeya, Prammananan, Therdsak, Tribuddharat, Chanwit, Thaipisuttikul, Iyarit, Doi, Norio, Leechawengwongs, Manoon, Chaiprasert, Angkana
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997844/
https://ncbi.nlm.nih.gov/pubmed/27297489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00539-16
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