A 3’UTR polymorphism marks differential KLRG1 mRNA levels through disruption of a miR-584-5p binding site and associates with pemphigus foliaceus susceptibility

Genetic variations mapping to 3’ untranslated regions (3’UTRs) may overlap with microRNA (miRNA) binding sites, therefore potentially interfering with translation inhibition or messenger RNA (mRNA) degradation. The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) l...

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Publicado no:Biochim Biophys Acta
Main Authors: Cipolla, Gabriel A., Park, Jong K., de Oliveira, Liana A., Lobo-Alves, Sara Cristina, de Almeida, Rodrigo C., Farias, Ticiana D. J., Lemos, Débora de S., Malheiros, Danielle, Lavker, Robert M., Petzl-Erler, Maria Luiza
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997811/
https://ncbi.nlm.nih.gov/pubmed/27424220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2016.07.006
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