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The Long and Winding Road: from the high affinity choline uptake site to clinical trials for malignant brain tumors

Malignant brain tumors are one of the most lethal cancers. They originate from glial cells and invade throughout the brain. Current standard of care involves surgical resection, radiotherapy and chemotherapy, and median survival is currently ~14–20 months post-diagnosis. Glioma tumors are highly inf...

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Bibliografische gegevens
Gepubliceerd in:Adv Pharmacol
Hoofdauteurs: Lowenstein, Pedro R., Castro, Maria G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997808/
https://ncbi.nlm.nih.gov/pubmed/27288077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apha.2016.03.002
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