Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer

Pancreatic cancer is highly lethal. Current research that combines radiation with targeted therapy may dramatically improve prognosis. Cancerous cells are characterized by unstable genomes and activation of DNA repair pathways, which are indicated by increased phosphorylation of numerous factors, in...

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Bibliographische Detailangaben
Veröffentlicht in:World J Gastroenterol
Hauptverfasser: Yang, Shih-Hung, Kuo, Ting-Chun, Wu, Hsu, Guo, Jhe-Cyuan, Hsu, Chiun, Hsu, Chih-Hung, Tien, Yu-Wen, Yeh, Kun-Huei, Cheng, Ann-Lii, Kuo, Sung-Hsin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Inc 2016
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997635/
https://ncbi.nlm.nih.gov/pubmed/27621574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i32.7275
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