Novel nanoscale bacteriophage-based single-domain antibodies for the therapy of systemic infection caused by Candida albicans

Candida albicans (C. albicans) is an important human commensal and opportunistic fungal pathogen. Secreted aspartyl proteinases (Saps) are a major virulence trait of C. albicans, and among these proteases Sap2 has the highest expression levels. It is possible that antibodies against Sap2 could provi...

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Published in:Sci Rep
Main Authors: Dong, Shuai, Shi, Hongxi, Cao, Donghui, Wang, Yicun, Zhang, Xintong, Li, Yan, Gao, Xiang, Wang, Li
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997605/
https://ncbi.nlm.nih.gov/pubmed/27558409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32256
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