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Chromatin boundary elements organize genomic architecture and developmental gene regulation in Drosophila Hox clusters

The three-dimensional (3D) organization of the eukaryotic genome is critical for its proper function. Evidence suggests that extensive chromatin loops form the building blocks of the genomic architecture, separating genes and gene clusters into distinct functional domains. These loops are anchored i...

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Détails bibliographiques
Publié dans:World J Biol Chem
Auteurs principaux: Ma, Zhibo, Li, Mo, Roy, Sharmila, Liu, Kevin J, Romine, Matthew L, Lane, Derrick C, Patel, Sapna K, Cai, Haini N
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997523/
https://ncbi.nlm.nih.gov/pubmed/27621770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v7.i3.223
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