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Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding
The post-translational modification S-sulfenylation functions as a key sensor of oxidative stress. Yet the dynamics of sulfenic acid in proteins remains largely elusive due to its fleeting nature. Here we use single-molecule force-clamp spectroscopy and mass spectrometry to directly capture the reac...
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| Gepubliceerd in: | Nat Commun |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996944/ https://ncbi.nlm.nih.gov/pubmed/27546612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12490 |
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