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A RANKL Wrinkle: Denosumab-Induced Hypocalcemia
The human monoclonal antibody denosumab inhibits osteoclast-mediated bone resorption by binding to receptor activator of nuclear factor κB ligand (RANKL), which is upregulated by tumor cells. Denosumab is indicated to prevent skeletal-related events (SREs) from osteoporosis and metastatic bone disea...
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| Publicado no: | J Med Toxicol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996783/ https://ncbi.nlm.nih.gov/pubmed/26987988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-016-0543-y |
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