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DNA methyltransferase inhibition increases efficacy of adoptive cellular immunotherapy of murine breast cancer

Adoptive T cell immunotherapy is a promising approach to cancer treatment that currently has limited clinical applications. DNA methyltransferase inhibitors (DNAMTi) have known potential to affect the immune system through multiple mechanisms that could enhance the cytotoxic T cell responses, includ...

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Pubblicato in:Cancer Immunol Immunother
Autori principali: Terracina, Krista P., Graham, Laura J., Payne, Kyle K., Manjili, Masoud H., Baek, Annabel, Damle, Sheela R., Bear, Harry D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996686/
https://ncbi.nlm.nih.gov/pubmed/27416831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1868-8
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