Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

Brief periods of sleep loss have long-lasting consequences such as impaired memory consolidation. Structural changes in synaptic connectivity have been proposed as a substrate of memory storage. Here, we examine the impact of brief periods of sleep deprivation on dendritic structure. In mice, we fin...

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Udgivet i:eLife
Main Authors: Havekes, Robbert, Park, Alan J, Tudor, Jennifer C, Luczak, Vincent G, Hansen, Rolf T, Ferri, Sarah L, Bruinenberg, Vibeke M, Poplawski, Shane G, Day, Jonathan P, Aton, Sara J, Radwańska, Kasia, Meerlo, Peter, Houslay, Miles D, Baillie, George S, Abel, Ted
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996653/
https://ncbi.nlm.nih.gov/pubmed/27549340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13424
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