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Embryonic Ethanol Exposure Dysregulates BMP and Notch Signaling, Leading to Persistent Atrio-Ventricular Valve Defects in Zebrafish

Fetal alcohol spectrum disorder (FASD), birth defects associated with ethanol exposure in utero, includes a wide spectrum of congenital heart defects (CHDs), the most prevalent of which are septal and conotruncal defects. Zebrafish FASD model was used to dissect the mechanisms underlying FASD-associ...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Sarmah, Swapnalee, Muralidharan, Pooja, Marrs, James A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996461/
https://ncbi.nlm.nih.gov/pubmed/27556898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161205
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