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Identification of Copy Number Aberrations in Breast Cancer Subtypes Using Persistence Topology

DNA copy number aberrations (CNAs) are of biological and medical interest because they help identify regulatory mechanisms underlying tumor initiation and evolution. Identification of tumor-driving CNAs (driver CNAs) however remains a challenging task, because they are frequently hidden by CNAs that...

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Detalhes bibliográficos
Publicado no:Microarrays (Basel)
Main Authors: Arsuaga, Javier, Borrman, Tyler, Cavalcante, Raymond, Gonzalez, Georgina, Park, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996377/
https://ncbi.nlm.nih.gov/pubmed/27600228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microarrays4030339
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