Imaging Renal Urea Handling in Rats at Millimeter Resolution Using Hyperpolarized Magnetic Resonance Relaxometry

In this study, in vivo T2 heterogeneity of hyperpolarized [(13)C,(15)N(2)]urea in rat kidney has been investigated. Selective quenching of the vascular hyperpolarized (13)C signal with a macromolecular relaxation agent revealed that a long T2 component of the [(13)C,(15)N(2)]urea signal originated f...

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Detalhes bibliográficos
Publicado no:Tomography
Main Authors: Reed, Galen D., von Morze, Cornelius, Verkman, Alan S., Koelsch, Bertram L., Chaumeil, Myriam M., Lustig, Michael, Ronen, Sabrina M., Bok, Robert A., Sands, Jeff M., Larson, Peder E. Z., Wang, Zhen J., Ardenkjær Larsen, Jan Henrik, Kurhanewicz, John, Vigneron, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: Grapho Publications, LLC 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996281/
https://ncbi.nlm.nih.gov/pubmed/27570835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18383/j.tom.2016.00127
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