Imaging Renal Urea Handling in Rats at Millimeter Resolution Using Hyperpolarized Magnetic Resonance Relaxometry

In this study, in vivo T2 heterogeneity of hyperpolarized [(13)C,(15)N(2)]urea in rat kidney has been investigated. Selective quenching of the vascular hyperpolarized (13)C signal with a macromolecular relaxation agent revealed that a long T2 component of the [(13)C,(15)N(2)]urea signal originated f...

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Pubblicato in:Tomography
Autori principali: Reed, Galen D., von Morze, Cornelius, Verkman, Alan S., Koelsch, Bertram L., Chaumeil, Myriam M., Lustig, Michael, Ronen, Sabrina M., Bok, Robert A., Sands, Jeff M., Larson, Peder E. Z., Wang, Zhen J., Ardenkjær Larsen, Jan Henrik, Kurhanewicz, John, Vigneron, Daniel B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Grapho Publications, LLC 2016
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996281/
https://ncbi.nlm.nih.gov/pubmed/27570835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18383/j.tom.2016.00127
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