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Perturbed meibomian gland and tarsal plate morphogenesis by excess TGFα in eyelid stroma

Transforming growth factor alpha (TGFα) belongs to the epidermal growth factor (EGF) family and is known to play an important role during eyelid morphogenesis. In this study, we showed that ectopic expression of TGFα in the stroma of Kera-rtTA/tet-O-TGFα bitransgenic mice results in precocious eye o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Dev Biol
Hauptverfasser: Dong, Fei, Liu, Chia-Yang, Yuan, Yong, Zhang, Yujin, Li, Wei, Call, Mindy, Zhang, Liyun, Chen, Yongxiong, Liu, Zuguo, Kao, Winston W.-Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996271/
https://ncbi.nlm.nih.gov/pubmed/26363126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.09.003
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