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Streptococcus oralis and Candida albicans Synergistically Activate μ-Calpain to Degrade E-cadherin From Oral Epithelial Junctions

Streptococcus oralis forms robust mucosal biofilms with Candida albicans that have increased pathogenic potential. In this study, using oral epithelial cultures, organotypic oral mucosal constructs, and a mouse model of oral infection, we demonstrated that S. oralis augmented C. albicans invasion th...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Xu, Hongbin, Sobue, Takanori, Bertolini, Martinna, Thompson, Angela, Dongari-Bagtzoglou, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996146/
https://ncbi.nlm.nih.gov/pubmed/27190184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw201
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