O-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesis

High-risk human papillomaviruses (HPVs) are causative agents of anogenital cancers and a fraction of head and neck cancers. The mechanisms involved in the progression of HPV neoplasias to cancers remain largely unknown. Here, we report that O-linked GlcNAcylation (O-GlcNAc) and O-GlcNAc transferase...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zeng, Qinghua, Zhao, Rui-Xun, Chen, Jianfeng, Li, Yining, Li, Xiang-Dong, Liu, Xiao-Long, Zhang, Wei-Ming, Quan, Cheng-Shi, Wang, Yi-Shu, Zhai, Ying-Xian, Wang, Jian-Wei, Youssef, Mariam, Cui, Rutao, Liang, Jiyong, Genovese, Nicholas, Chow, Louise T., Li, Yu-Lin, Xu, Zhi-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995993/
https://ncbi.nlm.nih.gov/pubmed/27482104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606801113
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