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Spatial organization of bacterial transcription and translation

In bacteria such as Escherichia coli, DNA is compacted into a nucleoid near the cell center, whereas ribosomes—molecular complexes that translate mRNAs into proteins—are mainly localized to the poles. We study the impact of this spatial organization using a minimal reaction–diffusion model for the c...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Castellana, Michele, Hsin-Jung Li, Sophia, Wingreen, Ned S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995950/
https://ncbi.nlm.nih.gov/pubmed/27486246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604995113
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