Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury

Macrophages are key regulators of fibrosis development and resolution. Elucidating the mechanisms by which they mediate this process is crucial for establishing their therapeutic potential. Here, we use experimental models of liver fibrosis to show that deficiency of the scavenger receptor, stabilin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rantakari, Pia, Patten, Daniel A., Valtonen, Joona, Karikoski, Marika, Gerke, Heidi, Dawes, Harriet, Laurila, Juha, Ohlmeier, Steffen, Elima, Kati, Hübscher, Stefan G., Weston, Chris J., Jalkanen, Sirpa, Adams, David H., Salmi, Marko, Shetty, Shishir
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995933/
https://ncbi.nlm.nih.gov/pubmed/27474165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604780113
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