Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury

Macrophages are key regulators of fibrosis development and resolution. Elucidating the mechanisms by which they mediate this process is crucial for establishing their therapeutic potential. Here, we use experimental models of liver fibrosis to show that deficiency of the scavenger receptor, stabilin...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Rantakari, Pia, Patten, Daniel A., Valtonen, Joona, Karikoski, Marika, Gerke, Heidi, Dawes, Harriet, Laurila, Juha, Ohlmeier, Steffen, Elima, Kati, Hübscher, Stefan G., Weston, Chris J., Jalkanen, Sirpa, Adams, David H., Salmi, Marko, Shetty, Shishir
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995933/
https://ncbi.nlm.nih.gov/pubmed/27474165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604780113
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