Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury

Macrophages are key regulators of fibrosis development and resolution. Elucidating the mechanisms by which they mediate this process is crucial for establishing their therapeutic potential. Here, we use experimental models of liver fibrosis to show that deficiency of the scavenger receptor, stabilin...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Rantakari, Pia, Patten, Daniel A., Valtonen, Joona, Karikoski, Marika, Gerke, Heidi, Dawes, Harriet, Laurila, Juha, Ohlmeier, Steffen, Elima, Kati, Hübscher, Stefan G., Weston, Chris J., Jalkanen, Sirpa, Adams, David H., Salmi, Marko, Shetty, Shishir
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995933/
https://ncbi.nlm.nih.gov/pubmed/27474165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604780113
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