Interleukin-17 Pathophysiology and Therapeutic Intervention in Cystic Fibrosis Lung Infection and Inflammation

Cystic fibrosis (CF) is characterized by an excessive neutrophilic inflammatory response within the airway as a result of defective cystic fibrosis transmembrane receptor (CFTR) expression and function. Interleukin-17A induces airway neutrophilia and mucin production associated with Pseudomonas aeru...

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Udgivet i:Infect Immun
Main Authors: Hsu, Daniel, Taylor, Patricia, Fletcher, Dave, van Heeckeren, Rolf, Eastman, Jean, van Heeckeren, Anna, Davis, Pamela, Chmiel, James F., Pearlman, Eric, Bonfield, Tracey L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995906/
https://ncbi.nlm.nih.gov/pubmed/27271746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00284-16
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