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Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages

CD40 is an important stimulator of autophagy and autophagic killing of Toxoplasma gondii in host cells. In contrast to autophagy induced by nutrient deprivation or pattern recognition receptors, less is known about the effects of cell-mediated immunity on Beclin 1 and ULK1, key regulators of autopha...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Liu, Elizabeth, Lopez Corcino, Yalitza, Portillo, Jose-Andres C., Miao, Yanling, Subauste, Carlos S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995900/
https://ncbi.nlm.nih.gov/pubmed/27354443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00101-16
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