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Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.

We have used expression cloning in Xenopus oocytes to isolate two different cDNAs encoding functional N-methyl-D-aspartate (NMDA) receptor subunits. The two receptors (NMDA-R1A and -R1B) display different pharmacologic properties as a consequence of alternative exon addition within the putative liga...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Nakanishi, N, Axel, R, Shneider, N A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1388270/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.18.8552
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