OPG-Fc but Not Zoledronic Acid Discontinuation Reverses Osteonecrosis of the Jaws (ONJ) in Mice

Osteonecrosis of the jaws (ONJ) is a significant complication of antiresorptive medications, such as bisphosphonates and denosumab. Antiresorptive discontinuation to promote healing of ONJ lesions remains highly controversial and understudied. Here, we investigated whether antiresorptive discontinua...

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Détails bibliographiques
Publié dans:J Bone Miner Res
Auteurs principaux: de Molon, Rafael Scaf, Shimamoto, Hiroaki, Bezouglaia, Olga, Pirih, Flavia Q, Dry, Sarah M, Kostenuik, Paul, Boyce, Rogely W, Dwyer, Denise, Aghaloo, Tara L, Tetradis, Sotirios
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995600/
https://ncbi.nlm.nih.gov/pubmed/25727550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2490
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