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Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet.

Hormone-sensitive lipase activity (HSL), which is found in the supernatant of centrifuged homogenates of lipolytically quiet isolated rat adipocytes, was greatly reduced in or absent from the supernatant of lipolytically stimulated cells. The lipase was purified 100- to 250-fold from the supernatant...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Egan, J J, Greenberg, A S, Chang, M K, Wek, S A, Moos, M C, Londos, C
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1528859/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.18.8537
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