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Staphylokinase has distinct modes of interaction with antimicrobial peptides, modulating its plasminogen-activation properties

Staphylokinase (Sak) is a plasminogen activator protein that is secreted by many Staphylococcus aureus strains. Sak also offers protection by binding and inhibiting specific antimicrobial peptides (AMPs). Here, we evaluate Sak as a more general interaction partner for AMPs. Studies with melittin, mC...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nguyen, Leonard T., Vogel, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995489/
https://ncbi.nlm.nih.gov/pubmed/27554435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31817
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