Low-dose ticagrelor yields an antiplatelet efficacy similar to that of standard-dose ticagrelor in healthy subjects: an open-label randomized controlled trial

Ticagrelor has a greater antiplatelet efficacy than clopidogrel but may be accompanied by an increased risk of bleeding. This study evaluated the antiplatelet effect and pharmacokinetic profile of low-dose ticagrelor in healthy Chinese volunteers. Thirty healthy subjects were randomized to receive s...

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Udgivet i:Sci Rep
Main Authors: Li, Pan, Gu, Ying, Yang, Yawei, Chen, Lizhi, Liu, Junmei, Gao, Lihong, Qin, Yongwen, Cai, Quancai, Zhao, Xianxian, Wang, Zhuo, Ma, Liping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995486/
https://ncbi.nlm.nih.gov/pubmed/27554803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31838
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