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The Role of Prostate Apoptosis Response-4 (Par-4) in Mycobacterium tuberculosis Infected Macrophages

Prostate apoptosis response-4 (Par-4) is a tumor suppressor protein that forms a complex with glucose-regulated protein 78 (GRP78) to induce apoptosis. Previously, we reported that ER stress-induced apoptosis is a critical host defense mechanism against Mycobacterium tuberculosis (Mtb). We sought to...

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Pubblicato in:Sci Rep
Autori principali: Han, Ji-Ye, Lim, Yun-Ji, Choi, Ji-Ae, Lee, Jung-hwan, Jo, Sung-Hee, Oh, Sung-Man, Song, Chang-Hwa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995434/
https://ncbi.nlm.nih.gov/pubmed/27552917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32079
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