Modulation of T-bet and Eomes during Maturation of Peripheral Blood NK Cells Does Not Depend on Licensing/Educating KIR

Peripheral natural killer (NK) cells upregulate T-bet and downregulate Eomes, the key transcription factors regulating NK cell maturation and function during the last maturation steps toward terminally differentiated effector cells. During this process, NK cells acquire killer immunoglobulin-like re...

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Vydáno v:Front Immunol
Hlavní autoři: Pradier, Amandine, Simonetta, Federico, Waldvogel, Sophie, Bosshard, Carine, Tiercy, Jean-Marie, Roosnek, Eddy
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995208/
https://ncbi.nlm.nih.gov/pubmed/27605928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00299
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