Enhanced protection against renal ischemia–reperfusion injury with combined melatonin and exendin-4 in a rodent model

We tested the hypothesis that combined treatment with melatonin, an anti-oxidant, and exendin-4, an anti-inflammatory agent, was superior to either alone for protecting the kidney from ischemia–reperfusion (IR) injury. Male adult Sprague-Dawley rats (n=40) were equally divided into group 1 (sham-ope...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Chang, Yi-Chih, Hsu, Shu-Yuan, Yang, Chih-Chao, Sung, Pei-Hsun, Chen, Yi-Ling, Huang, Tien-Hung, Kao, Gour-Shenq, Chen, Sheng-Yi, Chen, Kuan-Hung, Chiang, Hsin-Ju, Yip, Hon-Kan, Lee, Fan-Yen
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994899/
https://ncbi.nlm.nih.gov/pubmed/27037275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216642528
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