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Mitochondrial respiratory chain adaptations in macrophages contribute to antibacterial host defence

Macrophages tightly scale their core metabolism upon activation, but the precise regulation of the mitochondrial electron transport chain (ETC) and its functional implications are currently unknown. Here we show that recognition of live bacteria by macrophages transiently decreased the assembly of E...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Garaude, Johan, Acín-Pérez, Rebeca, Martínez-Cano, Sarai, Enamorado, Michel, Ugolini, Matteo, Nistal-Villán, Estanislao, Hervás-Stubbs, Sandra, Pelegrín, Pablo, Sander, Leif E., Enríquez, José A., Sancho, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994870/
https://ncbi.nlm.nih.gov/pubmed/27348412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3509
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