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Comparative preclinical evaluation of AS01 versus other Adjuvant Systems in a candidate herpes zoster glycoprotein E subunit vaccine

The candidate vaccine HZ/su is being developed to prevent herpes-zoster disease (HZ). HZ occurrence is attributed to declines in varicella-zoster virus (VZV) specific T-cell immunity. HZ/su contains VZV antigen, gE, and Adjuvant System AS01(B) (liposome-based formulation of MPL and QS-21). In clinic...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Fochesato, Michel, Dendouga, Najoua, Boxus, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994747/
https://ncbi.nlm.nih.gov/pubmed/26933767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1154247
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