Novel cationic peptide TP359 down-regulates the expression of outer membrane biogenesis genes in Pseudomonas aeruginosa: a potential TP359 anti-microbial mechanism

BACKGROUND: Antimicrobial peptides (AMPs) are a class of antimicrobial agents with broad-spectrum activities. Several reports indicate that cationic AMPs bind to the negatively charged bacterial membrane causing membrane depolarization and damage. However, membrane depolarization and damage may be i...

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Pubblicato in:BMC Microbiol
Autori principali: Dosunmu, Ejovwoke F., Chaudhari, Atul A., Bawage, Swapnil, Bakeer, Mona K., Owen, Donald R., Singh, Shree R., Dennis, Vida A., Pillai, Shreekumar R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994277/
https://ncbi.nlm.nih.gov/pubmed/27549081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0808-2
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